Geographical Distribution of Hepatitis E Virus Genotypes from Animals in China

Hepatitis E virus is a pathogen spread through the intestine and belongs to the hepevirus of the hepeviridae. HEV can mainly spread through the dung—the mouth way in the crowd, at the same time can be spread by animals. Research shows that many kinds of animals can be used as a natural reservoir of HEV. Judging from the molecular level, HEV is a non-enveloped single-strand RNA virus. It not only can cause sporadic cases of acute hepatitis E, but also can cause large-scale outbreaks. As genetic sequencing technology is more and more mature, HEV can be at least divided into four genotypes by sequencing its whole gene or partial gene and it has obvious geographical distribution in the crowd. From a global perspective: genotypeIis mainly in Asia and Africa. GenotypeIIis confined Mexico and Africa. Genotype III is widely distributed around the world. Genotype IV is mainly in Asian countries. Due to hepatitis e is a kind of zoonosis, therefore HEV genotype in animals should also have a certain distribution rule. In this paper, I have a review of all the literature on HEV genotypes in China from animals in order to sort out the geographical distribution of HEV genotypes and understand the geographical distribution of HEV genotypes in China about animals.